Mécanismes immunopathologiques associés aux granulomes et kystes odontogènes: revue générale

Authors

  • K Kalusokoma
  • J Duchateau
  • R Mayer
  • N Dourov

Abstract

The authors make a general survey of the immunopathological mechanisms involved in odontogenic cysts and granulomas. The dental pulp and the sound periapical tissues contain neither inflammatory nor immunoglobin-producing cells.

Dental decay associated with bacterial agression of the dental pulp and periapical tissues might induce a non-specific inflammation which subsequently becomes more specific. Immunoglobulins are present in fluid aspirates from odontogenic cysts and granulomas.

Several investigations have pointed out non-specific inflammatory mediators (including the C3 complement components), T lymphocytes (helpers and suppressors), B lymphocytes, Protein S-100 + cells (Langerhans cells).

The presence of immunoglobulins, immunocompetent cells and C3 complement components confirms that all constituents of both humoral and cell-mediated immunological reactions might play an essential role in the pathogenesis of osteolysis.

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Published

2020-04-17

Issue

Vol. 32 No. 2 (1989)

Section

Original Research Articles

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I hereby certify that the authors of the above manuscript have all:

1. Conceived, planned, and performed the work leading to the report, or interpreted the evidence presented, or both;

2. Written the report or reviewed successive versions and shared in their revisions; and

3. Approved the final version.

Further, I certify that:

1. This work has not been published elsewhere and is not under revision in another journal;

2. Humane procedures have been followed in the treatment of experimental animals (if applicable);

3. Investigations in humans was done in accordance with the ethical standards of the responsible committee on human experimentation or with the Helsinki Declaration (if applicable).

4. This paper has been carefully read by a native English speaker who is familiar with the field of work (this applies to authors who are not fluent in English); and

5. The copyright of the article is transferred from the authors to the Bulletin du Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie upon acceptance of the manuscript.