Comparative analyses among interfaces of some ceramic materials and bone in sheep

Authors

  • D Zaffe
  • A.M Gatti
  • G.P Poli
  • A Ravaglioli
  • A Krajewski

Keywords:

implantology, ceramics, bioactive materials

Abstract

Aim of this work is the evaluation of “in situ” implants in an animal model to study the interfaces that some ceramic materials for dental bone defects develop with bone and to check which material is more osteoconductive.

In a sheep’s jaw, eight holes were drilled and filled with six ceramic materials in granular shape. Two bilateral holes were left empty as reference. The ceramic materials were: porous tricalcium phosphate (TCP), porous hydroxylapatite (HA) and four bioactive glasses. The glasses differ for doping agents that affect the velocity of biodegradation in the living body.

Monthly radiographs were taken and the X-ray pictures analyzed by means of a Video Display Computer in order to quantify the optical density changes occured in the holes. After 4 month implantation, the segments of the jaw containing the materials were fixed in paraformaldehyde, embedded in methylmethacrylate and sectioned.

The results obtained under the microradiograph, the SEM and the X-ray microprobe showed a good bone repair only with TCP granules. A great degradation was seen in HA granules and particularly in glasses.

The degradation modified the structure and the composition of the glass granules, but it was not followed by a consequent bone deposition.

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Published

2020-04-17

Issue

Vol. 33 No. 2 (1990)

Section

Original Research Articles

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I hereby certify that the authors of the above manuscript have all:

1. Conceived, planned, and performed the work leading to the report, or interpreted the evidence presented, or both;

2. Written the report or reviewed successive versions and shared in their revisions; and

3. Approved the final version.

Further, I certify that:

1. This work has not been published elsewhere and is not under revision in another journal;

2. Humane procedures have been followed in the treatment of experimental animals (if applicable);

3. Investigations in humans was done in accordance with the ethical standards of the responsible committee on human experimentation or with the Helsinki Declaration (if applicable).

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5. The copyright of the article is transferred from the authors to the Bulletin du Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie upon acceptance of the manuscript.