Study of behaviour and endurance of Bioapatite® implanted in the periodontium of the dog (closed model)
Keywords:biomaterial, periodontium, filling material
The principle purpose of this study was to quantify endurance of the biomaterial Bioapatite ® implanted in periodontal structures of the dog (closed model), such quantification being established by means of indices (Endurance Index and Transformed Endurance Index) obtained as a result of data-processed analysis of histologic images. The investigation further aimed at studying the development of new cementum and the reconstruction of an attachment system. The study was conducted on eight dogs and 222 sections. New cementogenesis and the reconstruction of an attachment system are ohserved both in the test sites and the reference sites. Endurance of the biomaterial is statistically linked with time: the most substantial decrease in the endurance is observed between two and six months. Traces of the material subsist at month 9. The structure of material masses always remains lacunal on a microscopic scale (highest average Endurance Index observed during the investigation: 30.35%). An osteoid deposit can be continually detected as of the second month around crystalline deposits. Furhter, this type of deposit was noted on the periphery of the deposits implanted in ectopic position in the supracrestal connective tissue.
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1. Conceived, planned, and performed the work leading to the report, or interpreted the evidence presented, or both;
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Further, I certify that:
1. This work has not been published elsewhere and is not under revision in another journal;
2. Humane procedures have been followed in the treatment of experimental animals (if applicable);
3. Investigations in humans was done in accordance with the ethical standards of the responsible committee on human experimentation or with the Helsinki Declaration (if applicable).
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5. The copyright of the article is transferred from the authors to the Bulletin du Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie upon acceptance of the manuscript.