Influence of amalgam fillings on Hg levels and total antioxidant activity in plasma of healthy donors

Auteurs-es

  • M Pizzichini Department of Biomedical Sciences, University of Siena
  • M Fonzi Department of Biomedical Sciences, University of Siena, Italy
  • A Gasparoni Department of Biomedical Sciences, University of Siena
  • M Mencarelli Department of Biomedical Sciences, University of Siena, Italy
  • G Rocchi Department of Biomedical Sciences, University of Siena, Italy
  • V Kaitsas Department of Biomedical Sciences, University of Siena, Italy
  • L Fonzi Department of Biomedical Sciences, University of Siena, Italy

Résumé

In order to evaluate the influence of mercury (Hg) levels on antioxidant power in human plasma, 26 healthy people were evaluated by a dentist and their plasma analyzed for Hg content by atomic absorption and total antioxidant activity (TAA) by FRAP method. Hg plasma concentration correlated with number of amalgam restorations, suggesting that Hg released from fillings is a source of Hg in non-occupational exposed people. Fish consumption, in fact, showed no influence on Hg plasma levels, perhaps because Italian subjects examined in the present group used low quantity of fish at week or kinds of fish with light contamination. TAA negatively correlated with Hg plasma revealing a pro-oxidant role of Hg released from amalgam fillings.

Téléchargements

Publié-e

2008-12-20

Numéro

Vol. 43 No. 2 (2001)

Rubrique

Original Research Articles

Licence

I hereby certify that the authors of the above manuscript have all:

1. Conceived, planned, and performed the work leading to the report, or interpreted the evidence presented, or both;

2. Written the report or reviewed successive versions and shared in their revisions; and

3. Approved the final version.

Further, I certify that:

1. This work has not been published elsewhere and is not under revision in another journal;

2. Humane procedures have been followed in the treatment of experimental animals (if applicable);

3. Investigations in humans was done in accordance with the ethical standards of the responsible committee on human experimentation or with the Helsinki Declaration (if applicable).

4. This paper has been carefully read by a native English speaker who is familiar with the field of work (this applies to authors who are not fluent in English); and

5. The copyright of the article is transferred from the authors to the Bulletin du Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie upon acceptance of the manuscript.